Department of Chemical Engineering at the University of Michigan in Ann Arbor


2017 Publications:

  • Fish, Margaret B., Fromen, Catherine A., Lopez-Cazares, Genesis, Glinski, Alexander W. and Omolola Eniola -Adefesol. "Exploring deformable particles in vascular-targeted drug delivery: Softer is only sometimes better." Biomaterials 124 (2017): 169-179.
  • Sobczynski, Daniel J., and Omolola Eniola-Adefeso. "Effect of anticoagulants on the protein corona-induced reduced drug carrier adhesion efficiency in human blood flow." Acta Biomaterialia 48 (2017): 186-194.

2016 Publications:

  • Kelley, W. J.; Safari, H.; Lopez-Cazares, G.;Eniola-Adefeso, O. (2016). Vascular-targeted nanocarriers: design considerations and strategies for successful treatment of atherosclerosis and other vascular diseases. Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology. DOI: 10.1002/wnan.1414
  • Fromen, Catherine A;Fish, Margaret B; Zimmerman, Anthony; Eniola-Adefeso, Omolola."Evaluation of receptor‐ligand mechanisms of dual‐targeted particles to an inflamed endothelium." Bioengineering & Translational Medicine (2016).

2015 Publications:

  • Sobczynski, Daniel J; Fish, Margaret B; Fromen, Catherine A; Carasco-Teja, Mariana; Coleman, Rhima M; Eniola-Adefeso, Omolola. (2015). Drug carrier interaction with blood: a critical aspect for high-efficient vascular-targeted drug delivery systems. Therapeutic delivery. DOI: 10.4155/TDE.15.38
  • Namdee, K; Carrasco-Teja, M; Fish, M ; Charoenphol, P; Eniola-Adefeso, O. (2015). Effect of Variation in hemorheology between human and animal blood on the binding efficacy of vascular-targeted carriers. Scientific Reports. DOI: 10.1038/srep11631
  • Thompson, AJ; Eniola-Adefeso, O. (2015), Dense nanoparticles exhibit enhanced vascular wall targeting over neutrally buoyant nanoparticles in human blood flow. Acta Biomaterialia. DOI: 10.1016/j.actbio.2015.04.005
  • Namdee, K; Sobczynski, DJ; Onyskiw, PJ; Eniola-Adefeso, O. (2015). Differential Impact of Plasma Proteins on the Adhesion Efficiency of Vascular-Targeted Carriers (VTCs) in Blood of Common Laboratory Animals. Bioconjugate Chemistry. DOI: 10.1021/acs.bioconjchem.5b00474
  • Fish, M. B., Thompson, A. J., Fromen, C. A., & Eniola-Adefeso, O. (2015). Emergence and Utility of Nonspherical Particles in Biomedicine. Industrial & Engineering Chemistry Research. doi: 10.1021/ie504452j

2014 Publications:

  • van der Meel R,  M.H. Fens , P. Vader, W.W. van Solinge, O. Eniola-Adefeso, and R.M. Schiffelers. (2014) “Extracellular vesicles as drug delivery systems: Lessons from the liposome field.” J Control Release, 2014. In Press.
  • Sobczynski, D.J., P. Charoenphol, P. Onyskiw, K. Namdee, A.J. Thompson, and O. Eniola-Adefeso. (2014) “Plasma protein adsorption modulates drug carrier vascular wall adhesion.” PLoS One. 9 (9), e107408
  • Namdee, K., A.J. Thompson and O. Eniola-Adefeso. (2014)  “Evaluation of in vivo functionality and biodistribution of microspheroidal particles for vascular-targeted drug delivery in atherosclerosis.” Atherosclerosis, 2014. 237(1): 279-286

2013 Publications:

  • Heslinga, M.J., G.M. Willis, D. Sobzynski, A.J. Thompson and O. Eniola-Adefeso. (2013) “One-Step Fabrication of Agent-Loaded Biodegradable Microspheroids for Drug Delivery and Imaging Applications.”Colloids and Surfaces B: Biointerfaces. 2014. 116C: 55-62.
  • Onyskiw, Peter J; Eniola-Adefeso, Omolola. Effect of PEGylation on Ligand-Based Targeting of Drug Carriers to the Vascular Wall in Blood Flow.  Langmuir 29(35). 2013.  p. 11127-11134
  • Alex J. Thompson, Eric M. Mastria, and Omolola Eniola-Adefeso.  “The margination propensity of ellipsoidal micro/nanoparticles to the endothelium in human blood flow”. Biomaterials (2013), 34 (23), p 5863-71.
  • Katawut Namdee , Alex J. Thompson , Phapanin Charoenphol , and Omolola Eniola-Adefeso:  Margination Propensity of Vascular-Targeted Spheres from Blood Flow in a Microfluidic Model of Human Microvessels, Langmuir, 2013, 29 (8), pp 2530–2535.

2012 Publications:

  • Charoenphol, Phapanin; Onyskiw, Peter J; Carrasco-Teja, Mariana; Eniola-Adefeso, Omolola.  Particle-cell dynamics in human blood flow: Implications for vascular-targeted drug delivery. J. of Biomechanics 45(16). 2012. p.2822-2828.
  • Huang, R.B. and O. Eniola-Adefeso.  Differential expression of E-selectin in shear-cytokine stimulated endothelial cells. In preparation.

2011 Publications:

  • Charoenphol, P., S. Mocherla, D. Dubois, K. Namdee, D.J. Pinsky, O. Eniola-Adefeso. Targeting Therapeutics to the Vascular Wall in Atherosclerosis - Carrier Size Matters. Atherosclerosis, 2011.  Submitted.

2010 Publications:

  • Huang, R.B., S. Mocherla, M.J. Heslinga, P. Charoenphol, O. Eniola-Adefeso. Dynamic and cellular interactions of nanoparticles in vascular-targeted drug delivery. Molecular Membrane Biology, 2010. Mol Membr Biol, 2010.  27(4-6): 190-205.  Second most read article - summer 2010!
  • Eniola-Adefeso, O. Bringing Outreach Into the Engineering Classroom - A Mass and Heat Transfer Course Project. Chemical Engineering Education, 2010. In Print.

2009 Publications:

  • Charoenphol, P., R.B. Huang, O. Eniola-Adefeso. Potential role of size and hemodynamics in the efficacy of vascular-targeted spherical drug carriers. Biomaterials, 2009, 31(6): 1392-402.
  • Heslinga, M., E. Mastria, O. Eniola-Adefeso. Fabrication of biodegradable spheroidal microparticles for drug delivery applications. Journal of Controlled Release, 2009, 138(3): p.235-242.
  • Eniola-Adefeso, O., R.B. Huang, and C.W. Smith. Kinetics of LFA-1 mediated adhesion of human neutrophils to ICAM-1 - role of E-selectin signaling post-activation. Annals of Biomedical Engineering, 2009. 37(4): p.737-48.

2005 Publications:

  • Eniola, A.O. and D.A. Hammer. In vitro characterization of leukocyte mimetic for targeting therapeutics to the endothelium using two receptors. Biomaterials, 2005. 26(34): p. 7136-44.
  • Eniola, A.O., E.F. Krasik, L.A. Smith, S. Gang, and D.A. Hammer. I-domain of lymphocyte function-associated antigen-1 mediates rolling of polystyrene particles on ICAM-1 under flow. Biophysical Journal, 2005. 89: p. 3577-88.
  • Eniola, A.O. and D.A. Hammer. Characterization of biodegradable drug delivery vehicles with the adhesive properties of leukocytes II: Effect of degradation on targeting efficiency. Biomaterials, 2005. 26(6): p. 661-670.

2003 Publications:

  • Eniola, A.O., P.J. Willcox and D.A. Hammer. Quantifying Interplay between rolling and firm adhesion elucidated with a cell-free system engineered with two distinct receptor-ligand pairs. Biophysical Journal, 2003. 85(4): p. 2720-31.
  • Zhang, Y., A.O. Eniola, D.J. Graves , and D.A. Hammer. Specific Adhesion of Micron-Sized Colloids to Surfaces Mediated by DNA Hybridization. Langmuir, 2003. 19(17): p. 6905-11.
  • Eniola, A.O. and D.A. Hammer. Artificial polymeric cells for targeted drug delivery. J Controlled Release, 2003. 87(1-3): p. 18-22.

Older Publications:

  • Eniola, A.O., S.D. Rodgers and D.A. Hammer. Characterization of biodegradable drug delivery vehicles with the adhesive properties of leukocytes. Biomaterials, 2002. 23(10): p. 2167-77.
  • Eniola, A.O. and J.A. Lumpkin. Reducing metal-catalyzed oxidation during immobilize Cu-Iminodiacetic acid metal affinity chromatography. Proceedings National Conference of Undergraduate Research, 1998. Volume III: 989-91.