department of chemical engineering @ the university of michigan












Laboratory for Quantitative Signaling and Multi-scale Modeling

Welcome to the Linderman Group webpage!
We apply chemical engineering principles to the field of biology and medicine. Our research is focused on fundamental studies in cell biology and cellular signal transduction, which has a myriad of applications including drug discovery and tissue engineering.

Research Areas
A multi-scale and multi-system approach to understand granuloma formation in TB Models of receptor dynamics, signal transduction, and cell responses Agent-based modeling of chemotaxis, drug distribution, and vascularization in the tumor microenvironment
Media Coverage

We were featured by Michigan Engineering in an article titled Peering into the black box of tuberculosis!

Dr. Elsje Pienaar was featured in an article titled Fighting tuberculosis!

Recent News

May 2021

Congratulations to Melissa for passing the chemical engineering Doctoral Candidacy Exam!

January 2021

Check out Patrick's publication, Computational methods for characterizing and learning from heterogeneous cell-signaling data in Current Opinion in Systems Biology!


March 2021
January 2021

Congratulations to Dr. Bruna (Menezes) Scheuher for successfully defending her thesis!

October 2020
  • Congratulations to Dr. Joseph Cicchese on a successful thesis defense!

  • The group welcomes PhD student Melissa Calopiz!
September 2020
August 2020

Congratulations to Caitlin for beginning an Assistant Professor role at Gettysburg College!

July 2020

Phillip and Patrick just published Pre-existing Cell States Control Heterogeneity of Both EGFR and CXCR4 Signaling in Cellular and Molecular Bioengineering!

May 2020