Our collaborative work with Dr. Sun's group titled "Albumin nanoparticle containing a PI3Kγ inhibitor and paclitaxel in combination with α-PD1 induces tumor remission of breast cancer in mice" has been published in Science Translational Medicine. Luke designed and performed the CyTOF experiment and conducted the data analysis. Read more
Our collaborative work with Dr. Kahlenberg's group titled "Nonlesional lupus skin contributes to inflammatory education of myeloid cells and primes for cutaneous inflammation" has been published in Science Translational Medicine. Christine and Monem designed and performed the imaging CyTOF work. Read more
Our collaborative work with Dr. Kahlenberg's group titled "B cell signatures distinguish cutaneous lupus erythematosus subtypes and the presence of systemic disease activity" has been published in Frontiers in Immunology. Christine and Monem designed and performed the imaging CyTOF work. Read more
Bryan Coleman joined the Wen Lab as a new PhD student. Welcome!
Xiao Yin, Brett and Trang's paper titled "Virus-inspired Strategies for Cancer Therapy" has been published in Seminars in Cancer Biology. Read more
Andrew, Luke and Xiao Yin's paper titled "Virtual versus In-Person Presentation as a Project Deliverable Differentially Impacts Student Engaged-Learning Outcomes in a Chemical Engineering Core Course" has been published in Journal of Chemical Education.Read more
Our collaborative work with Dr. Zou's group titled "Liver metastasis restrains immunotherapy efficacy via macrophage-mediated T cell elimination" has been published in Nature Medicine. Monem designed and performed the CyTOF experiments. Read more
Trang Hoang joined the Wen Lab as a new PhD student. Welcome!
Our collaborative work with Dr. Gudjonsson's group titled "Contribution of plasma cells and B cells to hidradenitis suppurativa pathogenesis" has been published in JCI Insight. Christine and Monem designed and performed the CyTOF experiments and analysis. Read more
Xiao Yin has successfully passed her prelim exam. Congratulations!
Brett has successfully defended his thesis entitled "Development of a Yeast Biosynthetic Platform for Rapid Production and Engineering of an Influenza Virus-like Particle Vaccine". Congratulations, Dr. Hill!
Our collaborative work with Dr. Kamada's group titled "The Intermucosal Connection between the Mouth and Gut in Commensal Pathobiont-Driven Colitis" has been published in Cell. Brett and Monem performed the CyTOF experiments and analysis. Read more
Brett, Prabhu and Monem's paper titled "Yeast Intracellular Staining (yICS): Enabling High-throughput, Quantitative Detection of Intracellular Proteins via Flow Cytometry for Pathway Engineering" has been published in ACS Synthetic Biology. Read more
Our COVID-19 research and vaccine development has been featured by the Michigan Engineering! Read More
Luke and Andrew won the second place in the professional category of the AIChE k-12 STEM competition. Congratulations! Read more
Our VLP work has been featured by the Michigan Engineering! Read More
Andrew, Brett, Monem, Mason and Maddie's paper titled "Enhancing the Yield and Quality of Influenza Virus-like Particles (VLPs) Produced in Insect Cells by Inhibiting Cytopathic Effects of Matrix Protein M2" has been published in ACS Synthetic Biology. Read more
Prof. Wen has been awarded the Young Alumni Achievement Award by the ChBE Department at the University of Illinois Urbana-Champaign. Read more
Prof. Wen and Mason's work "Construction and Screening of an Antigen-Derived Peptide Library Displayed on Yeast Cell Surface for CD4+ T Cell Epitope Identification" has been published in Methods in Molecular Biology. Download PDF
Our work on whole-cell cooperative enzyme catalysis has been featured by the Michigan Engineering! Read more
Mason and Hui's paper "Elucidating structure–performance relationships in whole-cell cooperative enzyme catalysis" was published in Nature Catalysis. Congrats!
Andrew and Luke have been accepted to present their work at the AIChE Annual Meeting this year in Orlando, FL. Congratulations!
Mason and Luke's paper "Rapid Microsphere Assisted Peptide Screening (MAPS) of Promiscuous MHCII‐Binding Peptides in Zika Virus Envelope Protein" was published in AIChE Journal. Congrats!
Prof. Wen has been promoted to Associate Professor of Chemical Engineering.
Xiao Yin has successfully passed her Dissertation Candidacy Exam and become a PhD candidate. Congratulations, Xiao Yin!
Our paper with the Gudjonsson group was published in JCI Insight. Download PDF
Prof. Fei Wen has been awarded the UM College of Engineering David E. Liddle Research Excellence Award for 2018-2019. Read more
Prof. Wen, Mason, Brett, Andrew and Christine presented their work at the AIChE Annual Meeting held in Pittsburgh, PA.
Xiao Yin joined the Wen Lab as a new PhD student. Welcome!
Prof. Wen was named ACS Industrial & Engineering Chemistry Research's "2018 Class of Influential Researchers". Read more
Mason has successfully defended his thesis entitled "Quantitative Approach to Supramolecular Assembly Engineering for Isolating and Activating Antigen-Specific T Cells". Congratulations, Dr. Smith!
Christine has successfully passed her prelim exam. Congratulations!
Prof. Wen presented “A 40-parameter View of the Immune Landscape at Single-cell Resolution...and other Cool Things You Can Do With CyTOF” at the Taubman Technology Talks at the University of Michigan Frankel Cardiovascular Center.
Luke has successfully passed his prelim exam. Congratulations!
Christine, Brett and Andrew's paper "The Coming Age of Insect Cells for Manufacturing and Development of Protein Therapeutics" was published in I&EC Research. Congrats!
Luke and Mason's paper "Engineering Spatially Organized Multi-enzyme Assemblies for Complex Chemical Transformation" was published in ACS Catalysis. Congrats!
Mason's paper on Protein-Scaffold Directed Nanoscale Assembly of T Cell Ligands was published in ACS Synthetic Biology. Congrats!
Luke and Christine have both successfully passed their Dissertation Candidacy Exam and become PhD candidates. Congratulations, Luke and Christine!
Mason delivered a talk about his work on high throughput screening of antigenic peptides at the AIChE Annual Meeting.
Our paper with the Larson group was published in the Journal of Computational Chemistry. Download PDF
Luke has received an honorable mention by the NSF GRFP. Congratulations, Luke!
Prof. Wen was awarded the NSF CAREER Award. Read more
Brett and Andrew's paper "Engineering Virus-like Particles for Antigen and Drug Delivery" was published in Current Protein & Peptide Science. Download PDF
Christine and Luke joined the Wen Lab as new PhD students. Welcome!
Prof. Wen was awarded funding by NSF/BME for immune profiling of T cells towards reproducible and scalable biomanufacturing process in personalized cancer immunotherapy.
Prof. Wen was invited by NAE to present at the Frontiers of Engineering Education Symposium, Irvine, CA. Read more
Prof. Wen's paper reporting her pedagogical research on active student learning was published in Chemical Engineering Education. Download PDF
Hui's paper "Rare sugar production by coupling of NADH oxidase and L-arabinitol dehydrogenase" was published in RSC Advance. Download PDF
Andrew has successfully passed his Dissertation Candidacy Exam and become a PhD candidate. Congratulations, Andrew!
Hui's paper "Immobilization of Multi-biocatalysts in Alginate Beads for Cofactor Regeneration and Improved Reusability" was published in Journal of Visualized Experiments. Download PDF
Prof. Wen was awarded funding by NIH/ORIP for acquiring CyTOF (cytometry by time-of-flight) for investigating single cell proteomics.
Prof. Wen was award the 2016 Provost's Teaching Innovation Prize. Read more
Andrew Zak has received an honorable mention by the NSF. Congratulations, Andrew!
Prof. Wen has been awarded CRLT's Investigating Student Learning Grant, 2016, funded by the Center for Research on Learning and Teaching, the Office of the Vice Provost for Global and Engaged Education, and the College of Engineering.
Andrew has joined the lab as a new PhD student. Welcome!
Mason and Brett have successfully passed their prelim exam. Congratulations!
Mason and Brett have been accepted to present their work at the AIChE Annual Meeting this year in Salt Lake City, UT. Congratulations!
Prof. Wen was awarded funding by NSF/BME to engineer protein assemblies for personalized cancer immunotherapy.
Congratulations to Eugene and Stephanie who completed their B.S. in Chemical Engineering! We wish you all the best with graduate school.
Congratulations to Deepika who completed her M.S. in Chemical Engineering! We wish you all the best with your new job at GSK in Pennsylvania.
Congratulations to Eshita who completed her M.S. in Biomedical Engineering!
Eugene has been accepted into graduate school and will be attending Washington University, St. Louis for a PhD in Chemical Engineering. Congratulations, Eugene!
Stephanie has been accepted into graduate school and will be attending University of Illinois, Chicago for a PhD in Bioengineering. Congratulations, Stephanie!
Lester, Mingcheng and Vicki joined the lab as undergraduate students. Welcome!
Our paper with the Lee lab was published in the Biochemical Engineering Journal. Download PDF
Mason and Eshita’s review paper in Industrial and Engineering Chemistry Research is out. Congratulations! Download PDF
Alex Kukreja joined the Wen Group as a PIBS rotation student. Welcome!
Prof. Wen was awarded funding by NIH/NCI to develop new antigen presentation systems for cancer immunotherapy.
Brett and Mason each presented a poster at the Annual Blue/Green Seminar hosted at Michigan State University.
Prof. Wen presented a talk titled “Dissection of Human T-cell Heterogeneity at Single-cell Resolution Using Mass Cytometry” at the AIChE Annual Meeting held in Atlanta, GA.
Mason gave a talk at the 2014 MCubed Symposium titled "All in one detection of T cells: Specificity, Phenotype and Function"
Joao Costa joined the Protein Assembly Engineering lab as a Master's student. Welcome Joe!
Daniel has received a summer research internship in the Wen Research Group through the Summer Research Opportunity Program (SROP) at the University of Michigan. Congratulations and welcome, Dan!
Eugene and Stephanie have received summer research internships through the Summer Undergraduate Research Experience (SURE) program at University of Michigan. Congratulations, Eugene and Stephanie!
Stephanie attended the 10th Annual PEGS meeting held in Boston, MA, to present a poster titled “A Robust System for Producing Large Panels of Human MHCII-peptide Complexes”.
Prof. Wen has been invited to present a talk titled “Engineering Protein Assemblies for Health and Energy” at the 18th Annual Conference of Chinese American Chemical Society, Great Lakes Chapter, Abbott Park, IL.
Mason and Brett have both successfully passed their Dissertation Candidacy Exam and become PhD candidates. Congratulations, Mason and Brett!
Eugene has been awarded the A.H. White Scholarship. Congratulations, Eugene!
Eshita Khera joined the lab as a new Master's student. Welcome!
Prof. Wen has been named the Dow Corning Assistant Professor of Chemical Engineering. Read more
Prof. Wen received an R03 grant from NIH/NIAID to develop new tools for multiplexed T-cell repertoire profiling.
Deepika has been awarded the Dow Sustainability Fellowship for the year 2014. Congratulations, Deepika!
Syed Rizvi joined the lab as a Research Lab Specialist. Welcome!
Prof. Wen presented a talk titled “Multiplexed Detection of T cells: A 40-parameter View of Single Cells” at the AIChE Annual Meeting held in San Francisco, CA.
Mason Smith and Brett Hill joined the lab as new PhD students. Welcome!
Deepika Mutukuri joined the lab as a new Master's student. Welcome!
Prof. Wen has been invited to present a talk titled “Towards Multiplexed Single-cell Deep Immune Profiling: A 40-parameter View of Human Total T cells” in the Department of Microbiology & Immunology Seminar, University of Michigan.
Galang Ramadhan and Eugene Kim joined the lab as undergraduate students.
Prof. Wen received an instrument grant from the Office of Research and College of Engineering at UM.
Stephanie Tolbert joined the lab as an undergraduate student. Welcome!
Prof. Wen presented a poster at the Big 10 Women’s Workshop held in Milwaukee, WI.
Prof. Wen’s project in collaboration with Dr. Ronald Larson and Timothy Johnson has been funded by MCubed at UM.
Megan Egbert, Emily Carroll, and Evan Olexa joined the lab as undergraduate students. Welcome!
Prof. Wen has been invited to present a talk titled “Single-cell Deep Immune Profiling via CyTOF – The Next Generation of Cell Detection” at the Tumor Immunology & Host Response Program Meeting at the University of Michigan Comprehensive Cancer Center.
Protein-Assembly Engineering Lab is established in Department of Chemical Engineering at UM.
Cori Roth and Nathan Esperon joined the lab as new PhD students. Welcome!
Prof. Wen joined the Department of Chemical Engineering at UM.
Veronica Weisman joined the lab for the semester as an undergraduate student. Welcome!