Our collaborative work with Dr. Sun's group titled "Albumin nanoparticle containing a PI3Kγ inhibitor and paclitaxel in combination with α-PD1 induces tumor remission of breast cancer in mice" has been published in Science Translational Medicine. Luke designed and performed the CyTOF experiment and conducted the data analysis. Read more
April 2022
Our collaborative work with Dr. Kahlenberg's group titled "Nonlesional lupus skin contributes to inflammatory education of myeloid cells and primes for cutaneous inflammation" has been published in Science Translational Medicine. Christine and Monem designed and performed the imaging CyTOF work. Read more
Our collaborative work with Dr. Kahlenberg's group titled "B cell signatures distinguish cutaneous lupus erythematosus subtypes and the presence of systemic disease activity" has been published in Frontiers in Immunology. Christine and Monem designed and performed the imaging CyTOF work. Read more
October 2021
Bryan Coleman joined the Wen Lab as a new PhD student. Welcome!
June 2021
Xiao Yin, Brett and Trang's paper titled "Virus-inspired Strategies for Cancer Therapy" has been published in Seminars in Cancer Biology. Read more
Andrew, Luke and Xiao Yin's paper titled "Virtual versus In-Person Presentation as a Project Deliverable Differentially Impacts Student Engaged-Learning Outcomes in a Chemical Engineering Core Course" has been published in Journal of Chemical Education.Read more
January 2021
Our collaborative work with Dr. Zou's group titled "Liver metastasis restrains immunotherapy efficacy via macrophage-mediated T cell elimination" has been published in Nature Medicine. Monem designed and performed the CyTOF experiments. Read more
October 2020
Trang Hoang joined the Wen Lab as a new PhD student. Welcome!
Our collaborative work with Dr. Gudjonsson's group titled "Contribution of plasma cells and B cells to hidradenitis suppurativa pathogenesis" has been published in JCI Insight. Christine and Monem designed and performed the CyTOF experiments and analysis. Read more
September 2020
Xiao Yin has successfully passed her prelim exam. Congratulations!
Brett has successfully defended his thesis entitled "Development of a Yeast Biosynthetic Platform for Rapid Production and Engineering of an Influenza Virus-like Particle Vaccine". Congratulations, Dr. Hill!
July 2020
Our collaborative work with Dr. Kamada's group titled "The Intermucosal Connection between the Mouth and Gut in Commensal Pathobiont-Driven Colitis" has been published in Cell. Brett and Monem performed the CyTOF experiments and analysis. Read more
June 2020
Brett, Prabhu and Monem's paper titled "Yeast Intracellular Staining (yICS): Enabling High-throughput, Quantitative Detection of Intracellular Proteins via Flow Cytometry for Pathway Engineering" has been published in ACS Synthetic Biology. Read more
May 2020
Our COVID-19 research and vaccine development has been featured by the Michigan Engineering! Read More
November 2019
Luke and Andrew won the second place in the professional category of the AIChE k-12 STEM competition. Congratulations! Read more
September 2019
Our VLP work has been featured by the Michigan Engineering! Read More
Andrew, Brett, Monem, Mason and Maddie's paper titled "Enhancing the Yield and Quality of Influenza Virus-like Particles (VLPs) Produced in Insect Cells by Inhibiting Cytopathic Effects of Matrix Protein M2" has been published in ACS Synthetic Biology. Read more
Prof. Wen has been awarded the Young Alumni Achievement Award by the ChBE Department at the University of Illinois Urbana-Champaign. Read more
July 2019
Prof. Wen and Mason's work "Construction and Screening of an Antigen-Derived Peptide Library Displayed on Yeast Cell Surface for CD4+ T Cell Epitope Identification" has been published in Methods in Molecular Biology. Download PDF
Our work on whole-cell cooperative enzyme catalysis has been featured by the Michigan Engineering! Read more
Mason and Hui's paper "Elucidating structure–performance relationships in whole-cell cooperative enzyme catalysis" was published in Nature Catalysis. Congrats!
Andrew and Luke have been accepted to present their work at the AIChE Annual Meeting this year in Orlando, FL. Congratulations!
June 2019
Mason and Luke's paper "Rapid Microsphere Assisted Peptide Screening (MAPS) of Promiscuous MHCII‐Binding Peptides in Zika Virus Envelope Protein" was published in AIChE Journal. Congrats!
May 2019
Prof. Wen has been promoted to Associate Professor of Chemical Engineering.
Xiao Yin has successfully passed her Dissertation Candidacy Exam and become a PhD candidate. Congratulations, Xiao Yin!
April 2019
Our paper with the Gudjonsson group was published in JCI Insight. Download PDF
January 2019
Prof. Fei Wen has been awarded the UM College of Engineering David E. Liddle Research Excellence Award for 2018-2019. Read more
October 2018
Prof. Wen, Mason, Brett, Andrew and Christine presented their work at the AIChE Annual Meeting held in Pittsburgh, PA.
Xiao Yin joined the Wen Lab as a new PhD student. Welcome!
September 2018
Prof. Wen was named ACS Industrial & Engineering Chemistry Research's "2018 Class of Influential Researchers". Read more
Mason has successfully defended his thesis entitled "Quantitative Approach to Supramolecular Assembly Engineering for Isolating and Activating Antigen-Specific T Cells". Congratulations, Dr. Smith!
Christine has successfully passed her prelim exam. Congratulations!
Prof. Wen presented “A 40-parameter View of the Immune Landscape at Single-cell Resolution...and other Cool Things You Can Do With CyTOF” at the Taubman Technology Talks at the University of Michigan Frankel Cardiovascular Center.
August 2018
Luke has successfully passed his prelim exam. Congratulations!
July 2018
Christine, Brett and Andrew's paper "The Coming Age of Insect Cells for Manufacturing and Development of Protein Therapeutics" was published in I&EC Research. Congrats!
Luke and Mason's paper "Engineering Spatially Organized Multi-enzyme Assemblies for Complex Chemical Transformation" was published in ACS Catalysis. Congrats!
May 2018
Mason's paper on Protein-Scaffold Directed Nanoscale Assembly of T Cell Ligands was published in ACS Synthetic Biology. Congrats!
Luke and Christine have both successfully passed their Dissertation Candidacy Exam and become PhD candidates. Congratulations, Luke and Christine!
November 2017
Mason delivered a talk about his work on high throughput screening of antigenic peptides at the AIChE Annual Meeting.
September 2017
Our paper with the Larson group was published in the Journal of Computational Chemistry. Download PDF
March 2017
Luke has received an honorable mention by the NSF GRFP. Congratulations, Luke!
January 2017
Prof. Wen was awarded the NSF CAREER Award. Read more
November 2016
Brett and Andrew's paper "Engineering Virus-like Particles for Antigen and Drug Delivery" was published in Current Protein & Peptide Science. Download PDF
October 2016
Christine and Luke joined the Wen Lab as new PhD students. Welcome!
September 2016
Prof. Wen was awarded funding by NSF/BME for immune profiling of T cells towards reproducible and scalable biomanufacturing process in personalized cancer immunotherapy.
Prof. Wen was invited by NAE to present at the Frontiers of Engineering Education Symposium, Irvine, CA. Read more
August 2016
Prof. Wen's paper reporting her pedagogical research on active student learning was published in Chemical Engineering Education. Download PDF
July 2016
Hui's paper "Rare sugar production by coupling of NADH oxidase and L-arabinitol dehydrogenase" was published in RSC Advance. Download PDF
May 2016
Andrew has successfully passed his Dissertation Candidacy Exam and become a PhD candidate. Congratulations, Andrew!
April 2016
Hui's paper "Immobilization of Multi-biocatalysts in Alginate Beads for Cofactor Regeneration and Improved Reusability" was published in Journal of Visualized Experiments. Download PDF
March 2016
Prof. Wen was awarded funding by NIH/ORIP for acquiring CyTOF (cytometry by time-of-flight) for investigating single cell proteomics.
Prof. Wen was award the 2016 Provost's Teaching Innovation Prize. Read more
Andrew Zak has received an honorable mention by the NSF. Congratulations, Andrew!
November 2015
Prof. Wen has been awarded CRLT's Investigating Student Learning Grant, 2016, funded by the Center for Research on Learning and Teaching, the Office of the Vice Provost for Global and Engaged Education, and the College of Engineering.
October 2015
Andrew has joined the lab as a new PhD student. Welcome!
August 2015
Mason and Brett have successfully passed their prelim exam. Congratulations!
July 2015
Mason and Brett have been accepted to present their work at the AIChE Annual Meeting this year in Salt Lake City, UT. Congratulations!
June 2015
Prof. Wen was awarded funding by NSF/BME to engineer protein assemblies for personalized cancer immunotherapy.
May 2015
Congratulations to Eugene and Stephanie who completed their B.S. in Chemical Engineering! We wish you all the best with graduate school.
Congratulations to Deepika who completed her M.S. in Chemical Engineering! We wish you all the best with your new job at GSK in Pennsylvania.
Congratulations to Eshita who completed her M.S. in Biomedical Engineering!
April 2015
Eugene has been accepted into graduate school and will be attending Washington University, St. Louis for a PhD in Chemical Engineering. Congratulations, Eugene!
Stephanie has been accepted into graduate school and will be attending University of Illinois, Chicago for a PhD in Bioengineering. Congratulations, Stephanie!
February 2015
Lester, Mingcheng and Vicki joined the lab as undergraduate students. Welcome!
January 2015
Our paper with the Lee lab was published in the Biochemical Engineering Journal. Download PDF
Mason and Eshita’s review paper in Industrial and Engineering Chemistry Research is out. Congratulations! Download PDF
Alex Kukreja joined the Wen Group as a PIBS rotation student. Welcome!
December 2014
Prof. Wen was awarded funding by NIH/NCI to develop new antigen presentation systems for cancer immunotherapy.
Prof. Wen and her ChE342 undergraduate students welcomed 88 high school students in their classroom for their first-time U of M experience.
November 2014
Brett and Mason each presented a poster at the Annual Blue/Green Seminar hosted at Michigan State University.
Prof. Wen presented a talk titled “Dissection of Human T-cell Heterogeneity at Single-cell Resolution Using Mass Cytometry” at the AIChE Annual Meeting held in Atlanta, GA.
October 2014
Mason gave a talk at the 2014 MCubed Symposium titled "All in one detection of T cells: Specificity, Phenotype and Function"
September 2014
Joao Costa joined the Protein Assembly Engineering lab as a Master's student. Welcome Joe!
June 2014
Daniel has received a summer research internship in the Wen Research Group through the Summer Research Opportunity Program (SROP) at the University of Michigan. Congratulations and welcome, Dan!
May 2014
Eugene and Stephanie have received summer research internships through the Summer Undergraduate Research Experience (SURE) program at University of Michigan. Congratulations, Eugene and Stephanie!
Stephanie attended the 10th Annual PEGS meeting held in Boston, MA, to present a poster titled “A Robust System for Producing Large Panels of Human MHCII-peptide Complexes”.
Prof. Wen has been invited to present a talk titled “Engineering Protein Assemblies for Health and Energy” at the 18th Annual Conference of Chinese American Chemical Society, Great Lakes Chapter, Abbott Park, IL.
Mason and Brett have both successfully passed their Dissertation Candidacy Exam and become PhD candidates. Congratulations, Mason and Brett!
April 2014
Eugene has been awarded the A.H. White Scholarship. Congratulations, Eugene!
Eshita Khera joined the lab as a new Master's student. Welcome!
January 2014
Prof. Wen has been named the Dow Corning Assistant Professor of Chemical Engineering. Read more
Prof. Wen received an R03 grant from NIH/NIAID to develop new tools for multiplexed T-cell repertoire profiling.
Deepika has been awarded the Dow Sustainability Fellowship for the year 2014. Congratulations, Deepika!
December 2013
Syed Rizvi joined the lab as a Research Lab Specialist. Welcome!
November 2013
Prof. Wen presented a talk titled “Multiplexed Detection of T cells: A 40-parameter View of Single Cells” at the AIChE Annual Meeting held in San Francisco, CA.
October 2013
Mason Smith and Brett Hill joined the lab as new PhD students. Welcome!
Deepika Mutukuri joined the lab as a new Master's student. Welcome!
Prof. Wen has been invited to present a talk titled “Towards Multiplexed Single-cell Deep Immune Profiling: A 40-parameter View of Human Total T cells” in the Department of Microbiology & Immunology Seminar, University of Michigan.
September 2013
Galang Ramadhan and Eugene Kim joined the lab as undergraduate students.
August 2013
Prof. Wen received an instrument grant from the Office of Research and College of Engineering at UM.
May 2013
Stephanie Tolbert joined the lab as an undergraduate student. Welcome!
April 2013
Prof. Wen presented a poster at the Big 10 Women’s Workshop held in Milwaukee, WI.
February 2013
Prof. Wen’s project in collaboration with Dr. Ronald Larson and Timothy Johnson has been funded by MCubed at UM.
January 2013
Megan Egbert, Emily Carroll, and Evan Olexa joined the lab as undergraduate students. Welcome!
Prof. Wen has been invited to present a talk titled “Single-cell Deep Immune Profiling via CyTOF – The Next Generation of Cell Detection” at the Tumor Immunology & Host Response Program Meeting at the University of Michigan Comprehensive Cancer Center.
December 2012
Protein-Assembly Engineering Lab is established in Department of Chemical Engineering at UM.
October 2012
Cori Roth and Nathan Esperon joined the lab as new PhD students. Welcome!
September 2012
Prof. Wen joined the Department of Chemical Engineering at UM.
Veronica Weisman joined the lab for the semester as an undergraduate student. Welcome!
