WEN GROUP
PROTEIN-ASSEMBLY ENGINEERING LAB






Prof. Fei Wen, PhD

Associate Professor, Department of Chemical Engineering
Office: NCRC B028-G058W | Lab: NCRC B028-G101E
Ph. No: (734) 764-8723 | Email: feiwenum@umich.edu
Professional Experience:

Associate Professor, University of Michigan, 2019 - Present
Dow Corning Assistant Professor, University of Michigan, 2014 - 2016
Assistant Professor, Chemical Engineering, University of Michigan, 2012 - 2019
Post Doctoral Researcher, Stanford University, 2010 - 2012

Education:
PhD Chemical and Biomolecular Engineering - 2010, University of Illinois Urbana-Champaign, Advisor: Huimin Zhao
MS Chemical Engineering - 2006, University of Illinois Urbana-Champaign
BS Chemical Engineering - 2003, Tsinghua University, Beijing, China


Syed Monem Rizvi

Research Lab Specialist, Department of Chemical Engineering
Research Investigator, Department of Microbiology and Immunology, University of Michigan
PhD, University of Cambridge, UK


smrizvi@umich.edu

My research is focused on the development of influenza virus like particles using yeast cells and in engineering yeast cells that are capable of converting lignocellulosic biomass to alternative biofuels.

Prabhu Ponnandy

Postdoctoral Scholar, Department of Chemical Engineering
Postdoctoral Research Fellow, Department of Pathology and Immunology, The Hebrew University-Hadassah Medical School, Jerusalem, Israel
PhD, Konkuk University, Seoul, Korea


prabhup@umich.edu

Bioethanol is widely considered as an alternative to conventional non-renewable fossil fuels. My research project focuses on the production of Bioethanol from Metabolic Engineered yeast cells.

Brett Hill

Graduate Student, PhD Candidate, Department of Chemical Engineering
B.S. Chemical Engineering, Colorado State University

labrett@umich.edu

Virus-like particles represent the structure of a virus but lack the genetic material that allows viruses to reproduce. Their lack of a genome makes them excellent candidates for vaccines as they pose no risk of infection, but they accurately represent the antigenic surface proteins that elicit antibody production. The aim of my research is to design a high-throughput process for producing multi-protein virus-like particles.

Andrew Zak

Graduate Student, PhD Candidate, Department of Chemical Engineering
B.S. Chemical Engineering, Cleveland State University

zaka@umich.edu

My research project is focused on understanding the immune response of T cells to virus-like particles with different biomolecular designs (i.e. different flu strains or protein mutations). This work will allow for the production of more highly effective vaccines and may lead to the development of a universal influenza vaccine.

Luke Bugada

Graduate Student, PhD Candidate, Department of Chemical Engineering
B.C.E., Chemical Engineering, University of Dayton

lfbugada@umich.edu

Artificial antigen presentation systems (aAPS) mimic the process through which an immune response is generated and have the potential to treat a host of illnesses that involve the immune system such as infectious diseases, cancer, and autoimmune disorders. My project involves engineering protein scaffolds so they can selectively arrange multiple proteins for use in aAPS.

Christine Yee

Graduate Student, PhD Candidate, Department of Chemical Engineering
B.S., Chemical and Biomolecular Engineering, Georgia Institute of Technology

cmyee@umich.edu

My research focuses on the genome editing of insect cells to be used as an alternative host for manufacturing protein-based therapeutics.

Xiao Yin Ma

Graduate Student, PhD Candidate, Department of Chemical Engineering
B.S., Chemical and Biomolecular Engineering, Cornell University

maxy@umich.edu

My research focuses on developing quantitative approaches to engineer cellulosomes in yeasts to produce biofuels.

Reid Bailey

Undergraduate (Senior) Student, Department of Chemical Engineering

reidba@umich.edu

My research is focused on improving the strength of the bond between cohesion and dockerin proteins in cellulosomes for use in multi-enzyme complexes.

Sanjeev Raja

Undergraduate (Sophomore) Student, Department of Chemical Engineering

sanjeevr@umich.edu

Time-of-flight mass cytometry (CyTOF) enables high-throughput, deep phenotyping of immune cells at the single-cell level. My research focuses on developing and using computational, statistical, and machine learning techniques to analyze high-dimensional CyTOF data, with the goal of uncovering the biological mechanisms and subpopulations of interest in the immune response to influenza and other diseases.

Madison Bonahoom

Undergraduate (Junior) Student, Department of Chemical Engineering

mbona@umich.edu

Marisa Patel

Undergraduate (Sophomore) Student, Department of Chemical Engineering

pmarisa@umich.edu

Brian Yam

Undergraduate (Sophomore) Student, Department of Chemical Engineering

brianyam@umich.edu

Nicholas Ontko

Undergraduate (Sophomore) Student, Department of Chemical Engineering

nicontko@umich.edu

Current Members




ALUMNI


Mason Smith

Graduate Student, 2013-2018
Current Position: Systems Design Engineer, Advanced Technology Research at Thermo Fisher Scientific

Hui Gao

Visiting Scholar, Graduate Student, 2015-2018
Current Position:

Lester Lee

Undergraduate Student, 2015-2017
Current Position: Piping engineer at Vancouver Shipyards

Mingcheng Yi

Undergraduate Student, 2015-2017
Current Position: Master's Student, Stanford University

Vicki Chung

Undergraduate Student, 2015-2017
Current Position: Analytics Consultant (Big Data) at Rakuten, Inc.

Eshita Khera

Master's Student, 2014-2015
Current Position: Graduate Student, University of Michigan

Eugene Kim

Undergraduate Student, 2014-2015
Current Position: Graduate Student, Washington University, St. Louis

Stephanie Tolbert

Undergraduate Student, 2013-2015
Current Position: Graduate Student, University of Illinois Chicago

Deepika Mutukuri

Master's Student, 2013-2015
Current Position: Process Engineer at GlaxoSmithKline

Joao Costa

Master's Student, 2014
Current Position: Operations Engineer at BASF

Daniel Quevedo

Visiting Undergraduate Student, University of Miami, 2014
Current Position: Fulbright Fellow, Karlsruhe Institute of Technology

Cori Roth

Master's Student, 2012-2013
Current Position: Systems Integration Analyst at Accenture

Nathan Esperon

Master's Student, 2012-2013
Current Position: Graduate Student, Pennsylvania State University

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